THCPO, also known as THC-O-acetate or THC-O, is a synthetic cannabinoid and a chemical analogue of THC, the main psychoactive component of cannabis. THCPO is known to be significantly stronger than regular THC, reportedly up to three times stronger. This higher potency is due to the addition of an acetate group to the THC molecule, which may improve its ability to cross the blood-brain barrier.
THCPO is usually produced in the laboratory by modifying the THC extracted from cannabis plants. The process involves acetylation, where an acetyl group is introduced into the THC molecule, creating a new compound. This synthetic process raises significant legal and safety concerns:
Legality: THCPO operates in a legal grey area in many countries, including the United States. Although it is derived from state-approved hemp, its synthetic nature and psychoactive effects mean that it can be interpreted differently under both state and federal laws, similar to other synthetic cannabinoids.
Effects: Due to its potency, THCPO can produce strong psychoactive effects that can be more intense and longer lasting compared to those of THC. Users report experiences ranging from euphoria and altered perception to intense visual and auditory hallucinations.
Safety and health risks: There is limited research on the safety, therapeutic benefits or health risks of THCPO. The stronger potency and synthetic nature of THCPO could potentially lead to greater health risks, including an increased potential for negative psychological effects. There are concerns about possible toxic effects of the acetate group when inhaled or metabolised.
Due to these factors, THCPO is viewed with caution and potential users are advised to be aware of the legal risks and potential health consequences of its use.
